PrEP = Pre Exposure Prophylaxis.
This is when you take HIV medication before sex or any other activity that may expose you to HIV, to reduce the chance of getting HIV. The medication is usually taken daily by someone who is HIV negative, to reduce their chance of catching HIV. PrEP uses two HIV drugs (tenofovir and FTC) in one pill (called Truvada) before (and after) exposure.
PEP = Post Exposure Prophylaxis.
This is when you take HIV medication after an exposure to reduce the chance of getting infected with HIV.
PEPSE = PEP after Sexual Exposure
This is for example if you didn’t use a condom or if the condom broke or came off. It is used to separate this from PEP used after occupational exposure – for example when a health worker is scratched by a needle or syringe.